A new evidence overview suggests thaFor many people; caffeine is a way of life — constantly striving to consume an amount that will keep you perfectly alert, without impacting your sleep later on.

While it has been found to be packed with some nutritional benefits, caffeine isn’t all roses – and perhaps fatal.

The New York Post reports that Lachlan Foote, a 21-year-old from Australia died after adding just one teaspoon of caffeine powder to a protein shake. Reportedly, the young man blacked out and never regained consciousness.

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A coroner determined that Foote died of caffeine toxicity after unknowingly consuming a dangerous amount of the powder. Meanwhile, The Post reports that his family is calling to have the potentially lethal product banned in Australia.

The small amount of caffeine powder Foote incorporated into a smoothie, the Post reports, was the equivalent of up to 50 cups of coffee. Interestingly, the powder is often marketed as a dietary supplement in fitness communities. t few nutritional supplements or dietary interventions offer any protection towards cardiovascular ailment or dying, and a few may clearly motive harm. Findings from a meta-evaluation are published in Annals of Internal Medicine.

Current U.S. Nutritional suggestions recommend several healthful consuming patterns, such as Mediterranean and vegetarian diets, but they do no longer propose recurring complement use to reduce the chance for cardiovascular disorder or different continual diseases. Nonetheless, 1 out of 2 individuals in the U.S. Use some shape of dietary supplements with the suggested goal of improving their general health. With the book of new randomized records, it turned into not clear if dietary supplements and nutritional interventions play a position in preventing mortality and cardiovascular disorder.

Researchers from West Virginia University analyzed 277 randomized managed trials comprising nearly 1 million human beings to determine the results of sixteen special nutritional dietary supplements and eight nutritional interventions on mortality and cardiovascular effects in adults. The researchers located a few proofs that decreased salt consumption become defensive for all-motive mortality in members with normal blood stress and that omega-3, long-chain fatty acids were defensive for myocardial infarction and coronary coronary heart sickness. Folic acid confirmed a few protective gains for stroke. Conversely, combined calcium plus diet D intake improved the risk for stroke. Other supplements, along with multivitamins, selenium, diet A, vitamin B6, nutrition C, nutrition E, nutrition D on my own, calcium alone, folic acid, and iron, or such nutritional interventions as the Mediterranean weight loss plan, reduced saturated fats consumption, modified fat intake, decreased dietary fat consumption, and extended consumption of fish oil supplements, did now not seem to have significant impact on mortality or cardiovascular results.

According to the authors of an accompanying editorial from Scripps Research Translational Institute, the findings are confined through the first-class of the proof. For instance, geographic issues many of the research want to be considered. The mentioned advantage of folate seems to be in large part pushed with the aid of the inclusion of one look at from China, where a folate-rich weight loss plan is not routine. In addition, maximum research depends upon food diaries, which are based totally on someone’s reminiscence of what they fed on and therefore are not absolutely reliable. The authors say that for now, it’s affordable to preserve off on the usage of dietary supplements or food plan amendment for the motive of cardiovascular ailment prevention in all pointers and pointers.

Despite guidelines towards their use, opioids are frequently prescribed for ankle sprains. Physicians ought to be aware of current prescribing recommendations and understand which injuries are appropriate for opioid remedy. Findings from a brief research report are posted in Annals of Internal Medicine.

Ankle sprains are a common injury, but treatment techniques vary. Evidence-based total guidelines advocate ice, nonsteroidal anti-inflammatory drugs, and purposeful aid and exercise. Opioids have never been included in treatment recommendations. However, a current observe showed that about 25 percent of individuals with ankle sprains had been prescribed opioids in the emergency branch.

Researchers from the University of Michigan reviewed a medical health insurance claims database to become aware of the charge of opioid prescriptions inside 7 days after an ankle sprain and the charge of new, continual opioid use amongst these patients. More than 590,000 sufferers with ankle sprains have been protected in the analysis. Of them, 11. Nine percentage crammed an opioid prescription within 7 days of diagnosis, and eight.4 percent of those sufferers were still filling a prescription for an opioid ninety days after diagnosis. According to the researchers, those findings endorse that clinicians want to be conscious that opioids are commonly now not indicated for ankle sprains, and different evidenced-based measures are possibly underutilized.
Most sufferers hospitalized with pneumonia are handled with antibiotics for longer than vital and extra antibiotic remedy length has been related to patient-mentioned unfavorable events after discharge. Findings from a multi-health facility cohort examine are posted in Annals of Internal Medicine.

Pneumonia is the most commonplace motive for inpatient antibiotic use and overuse. Recent research, including a couple of randomized controlled trials and systematic reviews, have tested that shorter antibiotic therapy is secure and equally powerful for maximum patients with pneumonia — conversely, more prolonged remedy locations sufferers at hazard for antibiotic-associated adverse events.

Researchers from the University of Michigan and the Michigan Hospital Medicine Safety Consortium used information from an ongoing cohort take a look at of more than 6,000 patients hospitalized with community-obtained pneumonia or healthcare-associated pneumonia in forty three hospitals across Michigan to quantify extra antibiotic treatment length, decide elements associated with it, and examine its relationship with consequences. They discovered that -thirds of sufferers acquired excess antibiotic remedy, in particular because of excessive prescribing at discharge. Specifically, a prognosis of community-received pneumonia expected extra remedy notwithstanding evidence that most sufferers may be safely dealt with with 5 days of antibiotics. Excess antibiotic remedy duration become associated with affected person-reported negative activities after discharge.

According to the authors of an accompanying editorial, from Los Angeles County and USC Medical Center, those findings offer extra evidence that shorter duration is higher in terms of prescribing antibiotics for pneumonia.

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